Summary
The WISDOM study challenges annual mammograms as the default breast cancer screening. Researchers randomized more than 28,000 women aged 40–74 to either standard annual mammograms or personalized, risk‑based schedules that account for genetics, breast density, and other factors. Early results show that risk‑based screening detects cancer as safely as annual exams and may reduce advanced cases. Women at highest risk received more frequent imaging, while lower‑risk participants had less frequent or delayed screening without harming detection. The findings suggest tailoring mammography to individual risk could improve screening efficiency and safety, marking a potential shift from “one‑size‑fits‑all” guidelines.
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