Summary
Scientists may have found a way to reverse Alzheimer’s disease in mice by restoring balance in the brain’s energy system, challenging the long‑held view that the condition is irreversible. Researchers at University Hospitals Cleveland Medical Center discovered that levels of a vital energy molecule, NAD⁺, drop sharply in Alzheimer’s brains. By using the drug P7C3‑A20 to restore normal NAD⁺ levels in mouse models, they not only prevented disease onset but also reversed amyloid and tau accumulation and fully restored cognitive function. The findings provide “proof of principle” that some forms of dementia might be reversible, though human trials are still needed.
Fox News
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